Please use this identifier to cite or link to this item: https://repository.unad.edu.co/handle/10596/29887
Title: Ausencia de interferencias por anticuerpos heterófilos en la cuantificación de Troponina I Cardíaca, en pacientes con insuficiencia renal crónica terminal en tratamiento de hemodiálisis
Ausencia de interferencias por anticuerpos heterófilos en la cuantificación de Troponina I Cardíaca, en pacientes con insuficiencia renal crónica terminal en tratamiento de hemodiálisis
metadata.dc.creator: Almonacid, Carmen Cecilia
Cantillo Turbay, Jorge
Quintana, Janneth Carolina
Quiroga, Lorena Astrid
Parrado, Yolima Andrea
Keywords: Troponina I; cardiopatía urémica; anticuerpos heterófilos.
Publisher: Universidad Colegio Mayor de Cundinamarca
metadata.dc.relation: http://hemeroteca.unad.edu.co/index.php/nova/article/view/1048/1043
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metadata.dc.type: info:eu-repo/semantics/article
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Description: Absence of interferences for heterophilic antibodies in the quantification de cardiac Troponin I, in patients with terminal chronic renal inadequacy in hemodialysis treatment. The present study seeks to value the behavior of the addition of the blocking reagent of heterophilic antibodies (HBR), in the cardiac Troponin I quantification in patient with terminal chronicle renal inadequacy subjected to hemodialysis treatment. To each one of 70 patients with IRCt in hemodialysis treatment in the San Rafael University Hospital of Bogotá, they were taken a sample of serum and one of plasm heparanized in the pre dialysis, in which the TnIc concentrations were quantified with and without HBR addition, by means of the enzimoinmunoassay Axsym. The statistical test of Wilcoxon was used. The TnIc values in plasms and serums with and without the HBR addition didn't show significant differences (0.113 and 0.666 respectively), so much in the total of the patients as in those with chronic cardiac illness. Not having found differences in the TnIc values with and without HBR it takes us to think of the absence of heterophilic antibodies or in that the blocking reagent HBR doesn't have action in this population of patients.
El presente estudio pretende valorar el comportamiento de la adición del reactivo bloqueador de anticuerpos heterófilos (HBR) en la cuantificación de Troponina I cardíaca (TnIc) en pacientes con insuficiencia renal crónica terminal (IRCt) sometidos a tratamiento de hemodiálisis.Acada uno de los70 pacientes con IRCt en tratamiento de hemodiálisis en el Hospital Universitario Clínica San Rafael de Bogotá, se le tomó una muestra de suero y una de plasma heparinizado en la prediálisis, en las cuales se cuantificaron las concentraciones de TnIc con y sin adición de HBR, mediante el enzimoinmunoensayo Axsym. Se utilizó la prueba estadística de Wilcoxon. Los valores de TnIc en plasmas y sueros con y sin la adición de HBR no mostraron diferencias significativas (0.113 y 0.666 respectivamente), tanto en el total de los pacientes como en aquellos con enfermedad cardíaca crónica. El no haber encontrado diferencias en los valores de TnIc con y sin HBR nos lleva a pensar en la ausencia de anticuerpos heterófilos o en que el reactivo bloqueador HBR no tiene acción en esta población de pacientes.
metadata.dc.source: NOVA Biomedical Sciences Journal; Vol. 1, Núm. 1 (2003); 32-36
Nova; Vol. 1, Núm. 1 (2003); 32-36
NOVA Ciências Biomédicas Publicação; Vol. 1, Núm. 1 (2003); 32-36
2462-9448
1794-2470
URI: https://repository.unad.edu.co/handle/10596/29887
Other Identifiers: http://hemeroteca.unad.edu.co/index.php/nova/article/view/1048
10.22490/24629448.1048
Appears in Collections:Revista Nova

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