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https://repository.unad.edu.co/handle/10596/30119Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.creator | Amaya Guio, Jairo | - |
| dc.creator | Aristizabal Gutiérrez, Fabio Ancizar | - |
| dc.creator | Briceño Balcázar, Ignacio | - |
| dc.creator | Castillo Zamora, Marcos | - |
| dc.creator | García Robayo, Dabeiba Adriana | - |
| dc.creator | Salazar Jordan, Hernán David | - |
| dc.date | 2009-12-15 | - |
| dc.date.accessioned | 2019-11-08T21:25:15Z | - |
| dc.date.available | 2019-11-08T21:25:15Z | - |
| dc.identifier | http://hemeroteca.unad.edu.co/index.php/nova/article/view/427 | - |
| dc.identifier | 10.22490/24629448.427 | - |
| dc.identifier.uri | https://repository.unad.edu.co/handle/10596/30119 | - |
| dc.description | The free DNA in blood increases with some pathological conditions and certain physiological state. Several reports in the literature have highlighted that the free DNA in plasma or serum has clinical potential as a possible tool for the prognosis of human cancer. However, so far there are no reference values of healthy individuals with a representative sample size and no values have been reported for specific populations such as Bogota. That is why in this study we quantified the concentration of free DNA in healthy people of the Bogota population and thus established a normal range or reference value, the relationship between levels of free DNA and characteristics such as age and gender was further analyzed. The concentration of free DNA in the Bogota population was 0.72 ng/μL and no significant differences between ages and genders were found. | en-US |
| dc.description | El ADN libre en sangre incrementa con algunas condiciones patológicas y ciertos estados fisiológicos. Varios reportes en la literatura han resaltado que el ADN libre en plasma o suero tiene potencial clínico como una posible herramienta para el pronóstico de cáncer en humanos. Sin embargo, hasta el momento no se tienen valores de referencia de individuos sanos con un tamaño de muestra representativo y tampoco se han descrito valores para poblaciones específicas como la bogotana. Es por ello que en el presente estudio se cuantificó la concentración de ADN libre en personas sanas de la población bogotana y así se estableció un rango normal o valor de referencia, adicionalmente se analizó la relación entre los niveles de ADN libre y las características como edad y género. La concentración de ADN libre en la población bogotana fue de 0,72 ng/μL y no se encontraron diferencias significativas entre las edades y los géneros. | es-ES |
| dc.format | application/pdf | - |
| dc.language | spa | - |
| dc.publisher | Universidad Colegio Mayor de Cundinamarca | es-ES |
| dc.relation | http://hemeroteca.unad.edu.co/index.php/nova/article/view/427/1119 | - |
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| dc.rights | Copyright (c) 2009 NOVA Publicación en Ciencias Biomédicas | es-ES |
| dc.rights | http://creativecommons.org/licenses/by/4.0 | es-ES |
| dc.source | NOVA Biomedical Sciences Journal; Vol. 7, Núm. 12 (2009); 136-142 | en-US |
| dc.source | Nova; Vol. 7, Núm. 12 (2009); 136-142 | es-ES |
| dc.source | NOVA Ciências Biomédicas Publicação; Vol. 7, Núm. 12 (2009); 136-142 | pt-BR |
| dc.source | 2462-9448 | - |
| dc.source | 1794-2470 | - |
| dc.subject | Ciencias Naturales,Ciencias Biológicas,Genética y Herencia | es-ES |
| dc.subject | ADN libre; ALU; PCR tiempo-real; rango de referencia. | es-ES |
| dc.subject | ALU repeats; free DNA; real-time PCR; reference value. | en-US |
| dc.title | Quantification of free DNA in blood plasma of healthy volunteers in Bogotá population | en-US |
| dc.title | Cuantificación de ADN libre en plasma sanguíneo de voluntarios sanos en una población bogotana | es-ES |
| dc.type | info:eu-repo/semantics/article | - |
| dc.type | info:eu-repo/semantics/publishedVersion | - |
| dc.type | info:eu-repo/article/published | en-US |
| dc.type | info:eu-repo/article/published | es-ES |
| dc.type | info:eu-repo/article/published | pt-BR |
| Appears in Collections: | Revista Nova | |
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