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https://repository.unad.edu.co/handle/10596/46672| Title: | Meconium: Biomarker Vehicle of Expusure to Psychoactive Substances in Pregnant Women Meconio: vehiculo de biomarcadores de exposición a sustancias psicoactivas en gestantes |
| metadata.dc.creator: | Manrrique Lopez, Sandra Orjuela Velasco, Milena Puentes Garcia, Sonia |
| Keywords: | cocaine;etanol;fetal growth retardation fetal alcohol syndrome;marijuana;meconium;neonatal abstinence syndrome.;cocaína;etanol;marihuana;meconio;retardo del crecimiento fetal;síndrome alcohólico fetal;síndrome de abstinencia neonatal. |
| Publisher: | Universidad Colegio Mayor de Cundinamarca |
| metadata.dc.relation: | https://hemeroteca.unad.edu.co/index.php/nova/article/view/377/1179 |
| metadata.dc.format.*: | application/pdf |
| metadata.dc.type: | info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion reviewArticle reviewArticle reviewArticle |
| Description: | Children exposed to drugs in a prenatal way are a medical and social problem. A useful way to study this problem is by analyzing biological matrices, such as the meconium, which stores psychoactive substances or their metabolites. To determine its fetal exposure the most common system is the analysis of blood from the umbilical cord, urine from the mother, or urine from the new born. Meconium is inert and it is easily obtainable. It stores psychoactive substances or its metabolites from week 12 of gestation and they are fossilized in it until birth. It can be a very important instrument to investigate fetal exposure to several drugs of abuse. It is necessary to know the degree of fetal exposure to contribute to the prognosis and timely pathology treatment which, due to the lack of clinical relevant manifestations, can be overlooked and require the implementation of tests that use reliable biological matrices. La población infantil expuesta prenatalmente a drogas de abuso constituye un problema médico-social. Una forma útil de abordar este problema consiste en analizar matrices biológicas, como el meconio, que acumula sustancias psicoactivas o sus metabolitos. Su determinación de la exposición fetal se ha centrado en el análisis de sangre de cordón u orina materna o neonatal. El meconio es inerte y de fácil obtención, acumula sustancias psicoactivas o sus metabolitos desde la semana 12 de gestación donde quedan fosilizados hasta el nacimiento. Puede constituir un instrumento muy importante para investigar la exposición fetal a distintas drogas de abuso. Es necesario conocer el grado de exposición fetal para contribuir al diagnóstico y al tratamiento oportuno de patologías que por falta de manifestaciones clínicas relevantes, pasan inadvertidas y requieren la implementación de pruebas que utilicen matrices biológicas confiables. |
| metadata.dc.source: | NOVA Biomedical Sciences Journal; Vol. 5 No. 7 (2007); 76-83 Nova; Vol. 5 Núm. 7 (2007); 76-83 NOVA Ciências Biomédicas Publicação; v. 5 n. 7 (2007); 76-83 2462-9448 1794-2470 |
| URI: | https://repository.unad.edu.co/handle/10596/46672 |
| Other Identifiers: | https://hemeroteca.unad.edu.co/index.php/nova/article/view/377 10.22490/24629448.377 |
| Appears in Collections: | Revista Nova |
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