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https://repository.unad.edu.co/handle/10596/46770
Title: | Modelo Animal de Anemia Inducida por Flebotomía Crónica: Relación Funcional Entre Hierro y Eritropoyesis |
metadata.dc.creator: | Castillo Bohórquez MSC, Martha D´Anna, María Gaona Prieto, Suani García, Betina Giorgi, Gisela Mora Bautista MSC, Ana Isabel Roque, Marta Villarraga Muñoz, María del Mar |
Keywords: | Anemia;chronic phlebotomy;erythropoiesis;hematological studies;anemia;flebotomia crónica;eritropoyesis;estudios hematológicos. |
Publisher: | Universidad Colegio Mayor de Cundinamarca |
metadata.dc.relation: | https://hemeroteca.unad.edu.co/index.php/nova/article/view/517/994 |
metadata.dc.format.*: | application/pdf |
metadata.dc.type: | info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion info:eu-repo/article/published info:eu-repo/article/published info:eu-repo/article/published |
Description: | In the present work we studied the erythropoietic response to chronic phlebotomy-induced anemia and changes in cellular and systemic body iron distribution. Female mice (CF1 strain, n =32) were divided into control and experimental groups, following a paired experimental design. Iron distribution in spleen and liver during chronic phlebotomy was assessed by morphological studies and erythropoietic activity by hematological studies. Statistical differences were determined by Student test. The significance level was set at p En el presente estudio se analizo la respuesta eritropoyética a la anemia inducida por flebotomía crónica y los cambios en la distribución del hierro celular y sistémico del organismo. Ratones hembra de la cepa CF1 (n=32), se dividieron en dos lotes: control y experimental, siguiendo un diseño experimental pareado según su peso. La distribución del hierro en bazo e hígado durante la flebotomía crónica fue evaluada mediante estudios morfológicos y la actividad eritropoyética mediante estudios hematológicos. Las diferencias estadísticas se determinaron mediante Test Student. El nivel de significancia se fijó en p |
metadata.dc.source: | NOVA Biomedical Sciences Journal; Vol. 10 No. 17 (2012); 50-63 Nova; Vol. 10 Núm. 17 (2012); 50-63 NOVA Ciências Biomédicas Publicação; v. 10 n. 17 (2012); 50-63 2462-9448 1794-2470 |
URI: | https://repository.unad.edu.co/handle/10596/46770 |
Other Identifiers: | https://hemeroteca.unad.edu.co/index.php/nova/article/view/517 10.22490/24629448.517 |
Appears in Collections: | Revista Nova |
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