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Micosis por Pythium Insidiosum primer caso con diagnóstico definitivo en Colombia

Mycoses for Pythium insidiosum. First case with definitive diagnosis in Colombia

dc.contributorAl Dr. Gustavo Sanchez, Dr. Leonel Mendoza PhD, Dra. Raquel Vilela PhD. Investigadora en el Biomedical Laboratory Diagnostics Program - Michigan State Universityes-ES
dc.creatorAcero-Mondragón MDV. Esp. MSc, Edward Javier
dc.creatorDaniBotero Rosas, MD. PhD, Daniel Alfonso
dc.creatorMaldonado Arango MD MSc, María Inés
dc.date2013-06-15
dc.date.accessioned2019-11-08T21:25:04Z
dc.date.available2019-11-08T21:25:04Z
dc.identifierhttp://hemeroteca.unad.edu.co/index.php/nova/article/view/1021
dc.identifier10.22490/24629448.1021
dc.identifier.urihttps://repository.unad.edu.co/handle/10596/30043
dc.descriptionPythium insidiosum is a globally distributed fungus that causes a fungal infection called Pythio-sis is considered an emerging disease in humans and animals. A definitive diagnosis involves clinical, epidemiological, histopathological and molecular correlations. There are no reports of Pythiosis diagnosis involving all these correlations in Colombia. In this study were confirmed Phytiosis in two horses in rural area of Puerto Boyaca (Boyaca, Colombia) presenting single,itching, ulcerated, granulomatous lesions on their limbs with serosanguineous suppuration. Biopsies were analyzed pathologically and histopathologically. Polymerase Chain Reaction (PCR) was carried out from DNA extracted of paraffin blocks. This study report the first definitive diagnosis of phytiosis in Colombia based on the correlation between bio-geography area, the pathological and histopathological findings which included patterns like Splendore-Hoeplii and hyphae with rare septae (2.5 to 6.2 microns diameters of branching angled) along with sequenced DNA that showed 100% homology with the Pythium insidiosum sequence at the GenBank.en-US
dc.descriptionPythium insidiosum es un hongo distribuido globalmente causante de una micosis emergente llamada Pitiosis en personas y animales. El diagnóstico definitivo involucra correlación clínico epidemiológica, clínico patológica, histopatológica y molecular. En Colombia no existen antecedentes diagnósticos de Pitiosis con estas correlaciones. Pitiosis fue demostrada dos equinos de zona rural en Puerto Boyacá, Departamento de Boyacá-Colombia. Los equinos presentaron en extremidades lesiones únicas, pruriginosas, ulceradas, granulomatosas, alternada de masas sólidas con secreción serosanguinolenta. De las biopsias los hallazgos anatomopatológicos demostraron masas sólidas de aspecto coralino, las cuales se procesaron histopatológicamente. Los resultados correlacionados de biogeografía, las lesiones halladas en los equinos y en ellas los patrones histopatológicos de Splendore-Hoeplii, con hallazgos de hifas raramente septadas con diámetro de 2,5 a 6,2 micras en ramificación angulada, junto a la secuenciación del DNA extraído y comparado con el depositado para P.insidiosum en el GenBank permitió demostrar en todas las muestras una homología del 100% conformándose por primera vez el diagnóstico definitivo de Pitiosis en Colombia.es-ES
dc.formatapplication/pdf
dc.languagespa
dc.publisherUniversidad Colegio Mayor de Cundinamarcaes-ES
dc.relationhttp://hemeroteca.unad.edu.co/index.php/nova/article/view/1021/1018
dc.relation/*ref*/De Cock AW, Mendoza L, Padhye AA, Ajello L, Kaufman L. Pythium insidiosum sp. nov., the etiologic agent of pythiosis. J Clin Microbiol. 1987;25: 344-9.
dc.relation/*ref*/Mendoza L, Ajello L, McGinnis MR. Infection caused by the Oomycetous pathogen Pythium insidiosum. J Mycol Med. 1996;6:151-64.
dc.relation/*ref*/Krajaejun T, Sathapatayavongs, B, Chaiprasert, A. Srimuang, S. Do You Know Human Pythiosis? Infect Dis Antimicrob Agents. 2008;25(1):45-51.
dc.relation/*ref*/Mendoza L, Hernandez F, Ajello L: Life cycle of the human and animal oomycete pathogen Pythium insidiosum. J Clin Microbiol. 1993;31(11):2967–2973.
dc.relation/*ref*/Marques SA, Bagagli E, Sandra MG, Bosco Rosangela M P, Camargo Mariangela EA, et al. Pythium insidiosum: report of the first case of human infection in Brazil. An Bras Dermatol. 2006;81(5):483-5.
dc.relation/*ref*/Thianprasit M, Chaiprasert A, Imwidthaya P.Human pythiosis. Curr. Top. Med. Mycol.1996;7:43–54.
dc.relation/*ref*/Krajaejun T, Sathapatayavongs B, Pracharktam R. Clinical and epidemiological analyses of human pythiosis in Thailand. Clin Infect Dis 2006;43:569-76.
dc.relation/*ref*/Prasertwitayakij N, Louthrenoo W, Kasitanon N, Thamprasert K. Human pythiosis, a rare cause of arteritis: case report and literature review. Semin Arthritis Rheum. 2003;33:204-14.
dc.relation/*ref*/Heath JA , Kiehn TE, Brown AE, LaQuaglia MP, Steinherz LJ, Bearman G, et al. Pythium insidiosum pleuropericarditis complicating pneumonia in a child with jeukemia. Brief Report. CID. 2002;35:60-4.
dc.relation/*ref*/Pfaller MA, Diekema D J. Unusual Fungal and Pseudofungal Infections of Humans. J. Clin. Microbiol. 2005;43:1495-1504.
dc.relation/*ref*/Vanittanakom N, Supabandhu J,Khamwan C, Praparattanapan J, Thirach S, Prasertwitayakij N, et al. Identification of emerging human-pathogenic Pythium insidiosum by serological and molecular assay-based methods . J. Clin. Microbiol. 2004; 42(9): 3970-3974.
dc.relation/*ref*/Ribes JA, Vanover-Sams CL, Baker DJ. Zygomycetes in human disease Clin Microbiol Reviews. 2000;13(2):236–301.
dc.relation/*ref*/Bosco SM, Bagagli E, Araújo JP, Candeias JM, de Franco MF, Alencar ME, et al. Human pythiosis Brazil. Emerg Infect Dis. 2005;11:715-8.
dc.relation/*ref*/Santurio JM, Alves SH, Pereira DB, Argenta JS, Pitiose: uma micose emergente. Acta Scientiae Veterinariae. 2006;34(1):1-14.
dc.relation/*ref*/Miller RI. Investigations into the biology of three ‘phycomycotic’ agents pathogenic for horses in Australia. Mycopathologia. 1983;81:23–28.
dc.relation/*ref*/Stephens B A, Tarpley HL, Rakich PM, Latimer KS, Johnson ME, Bain PJ. Oomycosis: Pythiosis in the dog, horse and cat and Lagenidiosis in the dog. Accesado Julio 12 de 2008.Disponible de http://www.vet.uga.edu/VPP/clerk/stephens/index.php
dc.relation/*ref*/Biava J B, Ollhoff DB, Gonçalves RC, Biondo AW. Zygomycosis in equines. A review. Rev Acad Curitiba. 2007;(5)3: 225-230.
dc.relation/*ref*/Tabosa IM, Riet-Correa F, Nobre VMT, Azevedo EO J, Reis- Junior L, Medeiro RMT. Outbreaks of pythiosis in two flocks of sheep in northeastern Brazil. Vet Pathol. 2004;(41):412–415
dc.relation/*ref*/Alvin C, Camus A, Grooters M, Roberto F. Aquilar granulomatous pneumonia caused by Pythium insidiosum in a central American jaguar, Panthera onca. J Vet Diagn Invest. 2004;(16):567–571.
dc.relation/*ref*/Mendoza L, Arias M, Colmenarez V, Perazzo Y, Intestinal canine pythiosis in Venezuela confirmed by serological and sequencing análisis Mycopathologia. 2005;(159): 219–222.
dc.relation/*ref*/Miller RI, Olcott BM, Archer M. Cutaneous pythiosis in beef calves. J Am Vet Med Assoc. 1985 (186): 984–986.
dc.relation/*ref*/Schurko AM, Mendoza L, Arthur WA,. de Cock M, Bedard J, Klassen M. Development of a species-specific probe for Pythium insidiosum and the diagnosis of pythiosis. J Clin Microbiol. 2004;42(6):2411–2418.
dc.relation/*ref*/Santurio JM, Monteiro AB, Leal AT, Kommers GD de Sousa DS, Catto JB. Cutaneous pythiosis insidiosi in calves from the pantanal region of Brazil. Mycopathologia. 1998;(141):123–125.
dc.relation/*ref*/MacDonald E, Laurie Millward JP, Ravishankar NP. Biomechanical interaction between hyphae of two Pythium species (Oomycota) and host tissues. Fung Genet Biol. 2002;37:245-249.
dc.relation/*ref*/Ravishankar JP, Davis CM, Davis DJ, MacDonald E, Makselan SD, Millward L, et al. Mechanics of solid tissue invasion by the mammalian pathogen Pythium insidiosum. Fung Genet Biol. 2001;34:167–175.
dc.relation/*ref*/Krajaejun T, Kunakorn M, Pracharktam R, Chongtrakool P, Sathapatayavongs B, Chaiprasert A . et al. Identification of a novel 74-kilodalton immunodominant antigen of Pythium insidiosum recognized by sera from human patients with pythiosis. J Clin Microbiol. 2006;44(5):1674–1680.
dc.relation/*ref*/Mendoza L ,Nicholson V, Prescott JF. Immunoblot analysis of the humoral immune response to Pythium insidiosum in horses with pythiosis. J. Clin. Microbiol. 1992;30:2980–2983.
dc.relation/*ref*/Schurko A M, Mendoza L, de Cock A. W, Klassen G. R. Evidence for geographic clusters: Molecular genetic differences among strains of Pythium insidiosum from Asia, Australia and the Americas are explored. Mycologia. 2003; 95(2): 200–208.
dc.relation/*ref*/Santurio, JM, Catto JB, Comastr JA, Leal AT, Leal ABM. Ferida da moda: epidemiologia, diagnóstico, tratamento e experiencia com eqüinos infectados no pantanal. Comunicado Tecnico 34. 2004. Ministério da Agricultura, Pecuária e Abastecimento. 1.ed., Brazil . Accesado Julio 20 de 2008.Disponible de: http://www.cpap.embrapa.br/publicacoes/online/COT34.pdf
dc.relation/*ref*/Headley SA, Arruda Jr HN, Bett LV, Cutaneous pythiosis in a slaughtered horse: a case report. Arq. Inst. Biol. 2002;69(4):109-112.
dc.relation/*ref*/Poole HMM, Brashie MK, Equine cutaneous pythiosis. Compendium. 2003; 25(3):229-235.
dc.relation/*ref*/Luvizari FH, Lehmkuhl RC, Santos IW, Pitiose equina no estado do paraná – primeiro relato de caso Arch Vet Scien 2002;7(2):99-102.
dc.relation/*ref*/FischerJF,Pace LW, Turk JR, Kreeger JM, Miller MA,Gosser HS. Gastrointestinal pythiosis in Missouri dogs: eleven cases J Vet Diagn Invest. 1994; 6:380-382.
dc.relation/*ref*/Headley HA. Arruda Jr HN, Equine cutaneous pythiosis: a report of four cases. Ciência Rural. 2004;34(1):289–292.
dc.relation/*ref*/Pereira DSB, Santurio JM, AlvesSH, Argenta JS, Cavalheiro AS, et al Zoosporogênese in vitro entre isolados do oomiceto Pythium insidiosum. Ciência Rural. 2008;38 (1):143-147.
dc.relation/*ref*/Kaufman L, MendozaL, Standard PG. Immunodiffusion test for serodiagnosing subcutaneous zygomycosis. J Clin Micribiol. 1990;28:1887-1890.
dc.relation/*ref*/Rivierre C, Laprie C, Guiard-Marigny O, Bergeaud P, Berthelemy. M. Guillot M. Pythiosis in Africa. J. Emering Infect Dis. 2005;11(3):479-481.
dc.relation/*ref*/Kaufman L. Penicilliosis marneffei and pythiosis: Emerging tropical diseases. Mycopathologia. 1998;143:3–7.
dc.relation/*ref*/Badenoch PR, Coster DJ, Wetherall BL, Brettig HT, Rozenbilds AM, Drenth A, et al. Pythium insidiosum keratitis confirmed by DNA sequence analysis. Br J Ophthalmol. 2001;85:496.
dc.relation/*ref*/Mendoza L. Arias M, Colmenarez V, Perazzo Y Intestinal canine pythiosis in Venezuela confirmed by serological and sequencing análisis. Mycopathologia. 2005;159: 219–222
dc.relation/*ref*/Luis-León JJ, Pérez RC, Vivas JL, Mendoza L, Alonso FT. Confirmación de Pythium insidiosum como agente etiológico de la Granulomatosis Enzoótica Bovina mediante análisis de secuencia. Salus online. 2009;12 (Sup. 1):205-215.
dc.relation/*ref*/Plan de Desarrollo. Pueblo y Democracia 2008-2011 Municipio de Puerto Boyacá. Boyaca-Colombia. Acuerdo Nº 013 del 31 de Mayo de 2008. Accesado Mayo 8 de 2010Disponible en: http://puertoboyaca-boyaca.gov.co/apc-aa-files/36353061306433633731633432313233/PLAN_DE_DESARROLLO_2008_2011__PUERTO_BOYACA.pdf.
dc.relation/*ref*/Reis Júnior JL, Nogueira RHG, Estudo anatomopatológico e imunoistoquímico da pitiose em eqüinos naturalmente infectados. Arq Bras Meda Vet Zoot. 2002;54(4):358-365.
dc.relation/*ref*/World Health Organization (WHO). Calibrating the microscope. In: Basic laboratory methods in medical parasitology, 1991. Accesado Enero 22 de 2011Disponible de: http://whqlibdoc.who.int/publications/9241544104_(part1).pdf.
dc.relation/*ref*/Fredricks D N, Relman D A. Application of polymerase chain reaction to the diagnosis of infectious diseases. CID. 1999;29: 475–488.
dc.relation/*ref*/Reis JL, Quiroz-deCarvalho CC, Girao-Nogueira RH, Lemos LS, Mendoza L. Disseminated pythiosis in three horses. Vet Microbiol. 2003;96:289–295.
dc.relation/*ref*/Holdridge LR. Grenke WC. Hatheway WH. Liang T. Tosi JA. Forest environments in tropical life zones, a pilot study. Pergamon Press, Oxford. 1971. p 78-81
dc.relation/*ref*/5 year-old, female quarter horse. Enhanced wednesday slide Conference Online. Department of Defense Veterinary Pathology Residency. AFIP. March 21, 2007. Conf 18 - Case 3 . Accesado Julio 12 de 2008. Disponible de http://vp4.afip.org/wsco/wsc_showcase2.php?id=16 .
dc.relation/*ref*/Grooters AM, Whittington A, Lopez MK, Michelle N. Boroughs, AFR Evaluation of microbial culture techniques for the isolation of Pythium insidiosum from equine tissues.J Vet Diagn Invest. 2002;14:288–294.
dc.relation/*ref*/Miller RI, Campbell RSF. The comparative pathology of equine cutaneous phycomycosis. Vet. Pathol. 1984;21: 325-332.
dc.relation/*ref*/Monteiro Leal AB, Alexandre T, Leal, JM, Santurio GD, Kommerse J, Catto B. Pitiose eqüina no Pantanal brasileiro: aspectos clínicopatológicos de casos típicos e atípicos. Pesq. Vet. Bras. 2001;21(4):151-156.
dc.relation/*ref*/Sallis V, Pereira DB, Raffi MB. Pitiose cutânea em eqüinos: 14 casos Ciência Rural. 2003; 33(5)1-8.
dc.rightsCopyright (c) 2013 NOVA Publicación en Ciencias Biomédicases-ES
dc.rightshttp://creativecommons.org/licenses/by/4.0es-ES
dc.sourceNOVA Biomedical Sciences Journal; Vol. 11, Núm. 19 (2013); 65-72en-US
dc.sourceNova; Vol. 11, Núm. 19 (2013); 65-72es-ES
dc.sourceNOVA Ciências Biomédicas Publicação; Vol. 11, Núm. 19 (2013); 65-72pt-BR
dc.source2462-9448
dc.source1794-2470
dc.subjectPythium insidiosum; Pythiosis; diagnosis.en-US
dc.subjectPythyum insidiosum; Pitiosis; diagnóstico.es-ES
dc.titleMycoses for Pythium insidiosum. First case with definitive diagnosis in Colombiaen-US
dc.titleMicosis por Pythium Insidiosum primer caso con diagnóstico definitivo en Colombiaes-ES
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.typeinfo:eu-repo/article/publisheden-US
dc.typeinfo:eu-repo/article/publishedes-ES
dc.typeinfo:eu-repo/article/publishedpt-BR


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