Presence of Class 1 Integrons in Isolatedfrom the New-Born Units at Instituto Materno Infantil (Institute for the Mother and Child) in Bogotá

Pinilla MSC, Gladys; Muñoz Molina MSC, Liliana; Gallego, Eva Amanda; Chavarro B., Bibiana; Fandiño, Jennifer

dc.creator	Pinilla MSC, Gladys
dc.creator	Muñoz Molina MSC, Liliana
dc.creator	Gallego, Eva Amanda
dc.creator	Chavarro B., Bibiana
dc.creator	Fandiño, Jennifer
dc.date	2006-12-15
dc.date.accessioned	2022-02-22T19:57:04Z
dc.date.available	2022-02-22T19:57:04Z
dc.identifier	https://hemeroteca.unad.edu.co/index.php/nova/article/view/361
dc.identifier	10.22490/24629448.361
dc.identifier.uri	https://repository.unad.edu.co/handle/10596/46656
dc.description	Multiresistance to antimicrobial against Gram-positive bacteria, especially Staphylococcus epidermidis is a progressive problem in newborn-intensive care units. One of the recently described mechanisms of bacterial ressistance is the presence of integrons and gene cassettes. There are more than 9 types of integrons, out of which class 1 integron is the most frequently associated with strains causing hospital infections.In this study, presence of class 1 integrons in Staphylococcus epidermis was determined as coming from hemocultures and catheter points which caused nasocomial infection in newborn intensive care units of Instituto Materno Infantil in Bogotá, Colombia. From the 46 studied strains, intl1 gene was detected in 21 of them (45.7%). This finding, pioneer in bacterial strains isolated in newborns, suggests the necessity to look for gene cassette which give resistance to the different anti microbial entities to define nosocomial infection treatment schemes caused by these microorganisms.This is the first time mechanism of resistance to aminoglycoside and other antimicrobials in Colombian Gram positive strains is studied. We suggest that it is important to carry out assays with gene cassette for different antibiotics of nosocomial infection to provide a better treatment selection.	en-US
dc.description	a multiresistencia a los antibióticos por bacterias Gram positivas, especialmente el Staphylococcus epidermidis, constituye un problema creciente de salud pública en las unidades neonatales. Uno de los mecanismos de resistencia bacteriana recientemente descrito es la presencia de integrones y cassettes genéticos. Existen más de 9 clases de integrones, siendo el de clase 1 el que con mayor frecuencia se encuentra implicado en cepas causantes de infección hospitalaria.En este estudio, se determinó la presencia de integrones clase 1 en Staphylococcus epidermidis, provenientes de hemocultivos y puntas de catéter, que causaron infección nosocomial en las unidades neonatales del Instituto Materno Infantil de Bogotá, Colombia. De las 46 cepas estudiadas, se detectó la presencia del gen intI 1 en 21 de los aislamientos (45.7%). Este hallazgo, pionero en cepas bacterianas aisladas en neonatos, sugiere la necesidad de buscar cassettes genéticos que confieren resistencia a los diferentes antimicrobianos, para definir esquemas de tratamiento de infecciones nosocomiales causadas por estos microorganismos.	es-ES
dc.format	application/pdf
dc.format	application/pdf
dc.language	spa
dc.publisher	Universidad Colegio Mayor de Cundinamarca	es-ES
dc.relation	https://hemeroteca.unad.edu.co/index.php/nova/article/view/361/1187
dc.relation	https://hemeroteca.unad.edu.co/index.php/nova/article/view/361/1188
dc.rights	Derechos de autor 2006 NOVA Publicación en Ciencias Biomédicas	es-ES
dc.source	NOVA Biomedical Sciences Journal; Vol. 4 No. 6 (2006); 55-59	en-US
dc.source	Nova; Vol. 4 Núm. 6 (2006); 55-59	es-ES
dc.source	NOVA Ciências Biomédicas Publicação; v. 4 n. 6 (2006); 55-59	pt-BR
dc.source	2462-9448
dc.source	1794-2470
dc.subject	antimicrobial	en-US
dc.subject	gene cassette	en-US
dc.subject	genome bacterial	en-US
dc.subject	integrons	en-US
dc.subject	newborn	en-US
dc.subject	plasmids	en-US
dc.subject	antimicrobianos	es-ES
dc.subject	cassettes genéticos	es-ES
dc.subject	genoma bacteriano	es-ES
dc.subject	integrones	es-ES
dc.subject	neonato	es-ES
dc.subject	plásmidos.	es-ES
dc.title	Presence of Class 1 Integrons in Isolatedfrom the New-Born Units at Instituto Materno Infantil (Institute for the Mother and Child) in Bogotá	en-US
dc.title	Presencia de Integrones Clase 1 en Aislamientos de Staphylococcus epidermidis de las unidades de neonatología del Instituto Materno Infantil de Bogotá	es-ES
dc.type	info:eu-repo/semantics/article
dc.type	info:eu-repo/semantics/publishedVersion
dc.type	info:eu-repo/article/published	en-US
dc.type	info:eu-repo/article/published	es-ES
dc.type	info:eu-repo/article/published	pt-BR